LATE-AYA

Adolescents and Young Adults (AYAs) face a distinct set of challenges, including increased risks of secondary cancers, cardiovascular diseases, infertility, and mental health issueslike anxiety and depression. Oncology programs delivering care to AYAs provide survivors with individualised survivorship care plans at the end of treatment, to accompany follow-up with their primary care providers. However, adherence to these plans is often scarce, due to differences in AYA survivors’ age, sex, cancer treatment received, and socioeconomical conditions. Knowledge and understanding of such factors and of related late effects and impacts on quality of life is fundamental to providing effective survivorship care. The ubiquitous use of mobile devices by AYAs offers an opportunity to increase knowledge and understanding of AYAs cancer survivors’ health status and behaviours, allowing the modelling of late effects and quality of life trajectories in the different age subgroups. Digital health interventions overcome many barriers to AYA participation in survivorship programs. LATE-AYA seeks to fill this gap by empowering AYAs to better manage their health and well-being post-cancer, by developing an AI-driven digital phenotyping platform for managing late effects (LE) of cancer treatment. The project will implement a holistic, non-invasive approach through digital tools such as smartphones and wearables to monitor physical, psychological, and social well-being. The project will focus on preventive health behaviours, psychological support, and social reintegration, providing personalized care through digital interventions. LATE-AYA will contribute to long-term quality of life improvements, facilitate early detection of LE, and provide data-driven insights on the impact of lifestyle choices on health outcomes. This project is supported by a diverse consortium of European institutions and will leverage the UNCAN.eu platform to share data and models, fostering wider collaboration across the EU. This action is part of the Cancer Mission cluster of projects on “Quality of life (AYA)”.

Consortium

UNIVERSIDAD POLITECNICA DE MADRID (UPM), ESP
ISTITUTO EUROPEO DI ONCOLOGIA SRL (IEO), IT
FONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI (INT), IT
FUNDACIO PRIVADA PER A LA RECERCA I LA DOCENCIA SANT JOAN DE DEU (FSJD), ESP
SAMSUNG ELECTRONICS (UK) LIMITED (SAM), UK
DOTSOFT OLOKLIROMENES LISEIS TECHNOLOGIAS PLIROFORIKIS ANONIMI ETAIREIA (DOT), GR
UNIVERSIDAD DE GRANADA (UGR), ESP
UNIVERSITEIT TWENTE (UTW), NL
UNIVERSIDAD DE LA IGLESIA DE DEUSTO ENTIDAD RELIGIOSA (UDEU), ESP
C QUADRA SRL (CQ), IT
FUNDATIA YOUTH CANCER EUROPE (YCE), RO
KAUNO TECHNOLOGIJOS UNIVERSITETAS (KTU), LI
VIDYASOFT SRL (VS), IT
ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS (CERTH), GR
UNIVERSITA DEGLI STUDI DI TORINO (UNITO), IT
FUNDACIO PRIVADA INSTITUT D’INVESTIGACIO ONCOLOGICA DE VALLHEBRON (VHIO), ESP
NACIONALINIS VEZIO INSTITUTAS (NVI), LI
FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA (CNAO), IT